Producing Perfusion Machines for

Organ and Tissue Research

  • Normothermia
  • Machine Learning
  • Automation
  • Disinfection
  • Dialysis
  • Biochemistry
  • Cardiac, Endocrine, Digestive
  • Vascular Composite Allograft

We welcome scientific and commercial collaborators to reach out for more information.

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Functional Circulation

Innovative Perfusion Systems for Research

About Us

At Functional Circulation, we specialize in creating state-of-the-art research perfusion machines designed to advance the field of organ and tissue reaserch . Our passion for reliable and effective machines drives us to innovate, particularly in the area of infrequently studied structures. We collaborate with leading research teams to explore groundbreaking approaches that improve transplantation and physiology insights.

Product Lineup

Our product lineup includes the Model 35 bench top, Model 7 portable, and Model 41 versatile perfusion systems, each tailored to specific research needs. With a steadfast dedication to advancing research perfusion, we are proud to support groundbreaking studies and drive scientific progress.

Harnessing Machine Learning for Perfusion Management

Utilizing the latest advancements in machine learning, we have devised a novel approach to perfusion management. Our working prototype provides us with proprietary data from hundreds of simulated organ perfusion procedures, enabling near-real-time control and management of various parameters. Designed for easy integration with organ transplant operations, perfusion and preservation devices, and critical care environments, our control module outperforms current human-managed systems.

Our Commitment

Functional Circulation is committed to engineering excellence, providing researchers with reliable tools to advance their investigations. Through partnerships with renowned experts, we contribute to the development of new strategies in physiologic discovery through perfusion.

Products

Functional Circulation

Model 35

Benchtop Large

Functional Circulation

Model 7

Portable

M41 for web

Model 41

Benchtop Small

Features & Specifications

Features

Automatic Pressure Control
Normothermic
Full Size Organ Chamber
Sterilizable
Single Use Perfusion Circuit
Pressure, Flow, Temperature Display
Bubble Trap
Perfusate Sampling Port
Oxygenator
Available 2nd pump (sold separately)
Magnetic Stirrer
USB Datalogging
Cloud Data Upload
Hypothermic
Dialysis
pH Sensor
Gas Mixer

: Standard  : Optional

Specifications

Perfusion Mode Pulsatile Pulsatile Pulsatile
Pulse Rate 60 to 72 bpm 60 to 72 bpm 60 to 72 bpm
Pump Type Peristaltic Centrifugal Peristaltic
Pressure Setting 10 to 160 mmHg 80 mmHg 10 to 160 mmHg
Flow Rate Maximum 350 mL/min 350 mL/min 10 mL/min
Temperature 37 0C 34 0C 8 to 37 0C
Chamber Diameter 360 mm 360 mm 170 mm
Perfusate Volume 1 L 1 L 0.15 L
Oxygenator Membrane 2900 cm2 2900 cm2 80 cm2
Sterilization Method Gas Gas Gas
Cellular Technology LTE LTE LTE
Pressure Sensor Wheatstone Bridge Wheatstone Bridge Wheatstone Bridge
Temperature Sensor Thermistor Thermistor Thermistor
Battery Capacity 17 A-hr total
Battery type 2 x Lithium Ion
Running Time per Charge 7 hours
Warmup Time 2 hours 0.5 hours
Wall Plug Power 120 / 240 VAC 120 VAC 120 / 240 VAC
Battery Charging 12 hours
Weight 50 lbs.
Oxygen On-board 424 L (D-Size)

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